Kuijjer Lab

PUMA accepted in Bioinformatics

June 10, 2020

Our miRNA-target gene regulatory network reconstruction algorithm PUMA has been accepted for publication in Bioinformatics. We included an analysis on 38 tissues from GTEx to characterize tissue-specific regulation by miRNAs, identify miRNA functions, and their associations to disease. For more information, please see the publications and tools sections. The method is also available on NetZoo.

Using PUMA, we identified tissue-specific regulatory functions of miRNAs. Here, we highlight MIR517C, the miRNA with the highest over-representation of tissue-specific functions, and the functions it regulates in a tissue-specific manner.