November 01, 2022
We have posted a new version of our previous BioRχiv pre-print on large-scale network analysis by Tatiana. We modeled networks for individual soft-tissue sarcoma patients and identified large regulatory heterogeneity in leiomyosarcomas. To characterize this regulatory heterogeneity, Tatiana developed a new algorithm, called PORCUPINE. PORCUPINE is a permutation-based approach that uses Principal Components Analysis to identifies pathways that significantly contribute to regulatory heterogeneity in a patient population. We...
October 28, 2022
We have a new publication in the Journal of Pathology as part of a collaboration with David Adams from the Wellcome Sanger Institute. The work investigates the mutational landscape of primary cutaneous melanoma. More information on the publication can be found here.
October 06, 2022
We have a new publication in Frontiers in Digital Health as part of a collaboration with several groups through the NCI/DOE 2020 Ideas Lab: Toward Building a Cancer Patient "Digital Twin". The article describes five new approaches to build predictive cancer patient digital twins. More information on the publication can be found here.
August 31, 2022
We have a new publication in Cell Reports, as part of a collaboration with Victor Greiff, University of Oslo. Victor's team developed an approach to study immune receptor repertoires that uses similarity networks to derive a multidimensional picture of the immune repertoire landscape. More information on the publication can be found here.
August 10, 2022
We are very excited to announce that Joel Rodríguez Herrera has joined Kuijjer and Mathelier labs on a student internship. Joel is a Bachelor's student in Genomic Sciences from the National Autonomous University of Mexico (UNAM). He will be working on a joined project with Anthony Mathelier's group, predicting promoter-enhancer interactions using message passing approaches.