Recent Posts

• September 23, 2024

  New bioRχiv pre-print

  We have a new BioRχiv pre-print by Patrick, focused on single-sample network modeling to better understand the complex transcriptional changes in lung cancer. Patrick reconstructed patient-specific gene co-expression networks (GCNs) for 334 individuals using LIONESS on mutual information networks. This revealed six new LUAD subtypes, each with unique biological features. Further analysis identified 12 key genes whose network patterns were linked to patient survival. Patrick's findings highlight the...

• September 03, 2024

  New group member

  We are very excited to announce that Siep van Amsterdam has joined Kuijjer group for a 9-month thesis internship. Siep is student in Bioinformatics at Leiden University of Applied Sciences. During his stay at NCMM, he will work on creating a resource of reference healthy cell networks using SCORPION, under the supervision of Nolan and Ladislav.

• September 02, 2024

  Keynote lecture

  Marieke will be giving a keynote lecture at CIBB 2024 on September 6. The topic will be understanding cellular complexity in cancer through personalized regulatory network modeling.

• July 19, 2024

  New publication

  We are happy to announce that Debora's whole genome analysis of multi-tissue osteosarcoma samples is now published in Genes Chromosomes & Cancer! For more details, see the news item on the pre-print. The publication can be accessed here. Please also refer to the publications section.

• July 18, 2024

  Keynote lecture

  Marieke recently gave a keynote lecture at the closing meeting of TranSYS, The Translational Science and Systems medicine in Personalized Medicine European Training Network (ETN). Click here for a newsarticle from NCMM covering the topic.