Recent Posts

• August 19, 2020

  Frontiers Research Topic

  Together with Kimberly Glass from the Channing Division of Network Medicine, Brigham and Women's Institute, Harvard Medical School and Maud Fagny from Eco-Anthropologie, National Museum of Natural History, CNRS, University of Paris, we are editing a Research Topic in Frontiers on Applications and Methods in Genomic Networks. Our goal in this Research Topic is to provide a collection of articles that (1) examine or propose innovative and novel...

• August 13, 2020

  New publication

  We recently published a "Cancer Research Highlights" article in Cancer Research in which we discuss a recent study on state transitions in cancer. Please see our publications page for more information.

• July 03, 2020

  Presentation at NetBioMed2020

  We're excited to announce that we'll be attending the NetBioMed2020, where Marieke will give an invited talk. The conference will be a virtual event on September 17, as a sattelite to the NetSci2020 meeting.

• June 24, 2020

  New publication

  We have a new publication in Cell Reports. We modeled 8,279 individual sample gene regulatory networks representing 29 tissues using PANDA and LIONESS. Using network analysis, we found that gene regulatory processes vary by sex across tissues and that many transcription factors have sex-biased targeting patterns. Differential gene expression between sexes is relatively modest on the non-sex chromosomes, generally occurring in tissues and pathways already known for...

• June 17, 2020

  New BioRχiv pre-print

  We have a new BioRχiv pre-print, which was work in collaboration with researchers from the University of Paris-Saclay, INRAE, CNRS. Maud Fagny modeled enhancer-driven regulatory networks for different maize tissues. This led to the discovery of tissue-specific regulatory modules involved in distinct functions related to the biology of each tissue, as well as the identification of transposable elements that have shaped the regulatory network in each...